Download E-books Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book) PDF

By Victor K. McElheny

Drawing the Map of Life is the dramatic tale of the Human Genome venture from its origins, in the course of the race to reserve the three billion subunits of DNA, to the surprises rising as scientists search to use the molecule of heredity. It’s the 1st account to deal intensive with the highbrow roots of the venture, the motivations that drove it, and the hype that frequently masked real triumphs.

Distinguished technology journalist Victor McElheny deals shiny, insightful profiles of key humans, equivalent to David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny additionally indicates that the Human Genome undertaking is a awesome instance of ways new concepts (such as limit enzymes and sequencing tools) usually arrive first, shaping the questions scientists then ask.

Drawing on years of unique interviews and reporting within the internal circles of organic technology, Drawing the Map of Life is the definitive, up to date tale of today’s maximum medical quest. nobody who needs to appreciate genome mapping and the way it truly is reworking our lives can have enough money to overlook this book.

Show description

Read or Download Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book) PDF

Similar Biology books

Signature in the Cell: DNA and the Evidence for Intelligent Design

“Signature within the mobile is a defining paintings within the dialogue of life’s origins and the query of no matter if existence is a made from unthinking topic or of an clever brain. in the event you disagree with identity, the robust case Meyer offers can't be missed in any sincere debate. if you happen to could be sympathetic to identification, at the fence, or basically curious, this e-book is an interesting, eye-opening, and infrequently eye-popping learn” — American Spectator Named one of many most sensible books of 2009 by means of the days Literary complement (London), this debatable and compelling ebook from Dr.

BSCS Biology: A Molecular Approach, Student Edition

A finished, inquiry-based method of biologyBSCS Biology: A Molecular technique (Blue model) demanding situations talented and honor scholars to imagine scientifically, to combine techniques, to research information, and to discover complicated concerns. This research-based software, constructed with investment from the nationwide technological know-how origin, helps an inquiry method of biology.

The Song of the Dodo: Island Biogeography in an Age of Extinctions

In Darwin's time, island biogeography used to be the technological know-how that opened Victorian minds to the beauty of evolution. this day with the entire world's wild panorama being chopped into island-like fragments, it is the technology of jeopardy and extinction. This e-book combines technological know-how, old narrative and commute.

Fragment Based Drug Design, Volume 493: Tools, Practical Approaches, and Examples (Methods in Enzymology)

There are various first-class experiences on fragment-based drug discovery (FBDD), yet there are so far no hand-holding publications or protocols with which you'll embark in this orthogonal method of supplement conventional excessive throughput screening methodologies. This tools in Enzymology quantity deals the instruments, sensible techniques, and hit-to-lead examples on find out how to behavior FBDD displays.

Extra resources for Drawing the Map of Life: Inside the Human Genome Project (A Merloyd Lawrence Book)

Show sample text content

He additional that “the complete paradigm of genetics is reversed. ” Now, geneticists have been free of discovering genes by way of trying to find the results of small mutations in DNA. in its place, they can “take the full series of an organism and paintings down from that to its genes, that's what geneticists were dreaming of for a very long time. ” The tricky Venter used to be heightening the drama. Collins referred to as the luck “a major milestone. ” Watson stated, “I imagine it’s an exceptional second in technology. With 1000 genes pointed out, we're commencing to see what a mobile is. ” He wrote that the success used to be “clearly a landmark within the background of biology. ” lower than years later, a British observer recalled that the realm were skeptical, yet Venter had replaced microbial genetics “overnight” and opened the right way to many new thoughts for attacking infections. the hot enthusiasm speedy spurred new festival. In 1996, a shocked NIH paid for an attempt at TIGR to series a hugely infectious pressure of the tuberculosis bacillus that had lately triggered a deadly disease in a garments manufacturing unit in Tennessee. yet Britain’s Wellcome belief additionally jumped in, with cash for a sequencing force on a long-studied assorted pressure of tuberculosis, performed in Cambridge, England, and Paris. In 1996, the eu attempt got here in a little sooner than TIGR’s. 32 after all, the sequencing tale was once by no means all Venter, for all time. within the spring of 1996, a world consortium of a few six hundred scientists in approximately seventy laboratories in Europe, Canada, the U.S., and Japan introduced good fortune in a seven-year force to spell out the complete 12 million letter series of baker’s yeast. Yeast had a few 6,000 genes (of which many resembled human genes) arrayed in 16 chromosomes. The study were parceled out in keeping with a “gentleman’s agree- SCALING UP 113 ment” to not compete. This classical device of genetics turned the biggest organism but sequenced, some distance longer than the laboratory bacterium E. coli or the bacterium Helicobacter pylori (recently stumbled on to be the important reason behind ulcers). Yeast used to be the 1st eukaryote, a mobile with a nucleus, to have its genome deciphered. Ron Davis, whose Stanford laboratory had performed 7 percentage of the task, stated, “Until now, the yeast genome has been a black box,” yet now “we recognize what’s there, and what’s now not there. ” Collins crowed, “The yeast genome is toward the human genome than something thoroughly sequenced up to now. ” If the human genome should be in comparison to sending Apollo astronauts to the moon, Collins stated, the yeast series was once similar to John Glenn’s Mercury flight round earth in 1962. Now an severe attempt may well start to figure out the services of yeast genes— as a step towards doing an analogous in people. Cooperation sprang up along competition. TIGR used to be already playing the consortium to series a fast-growing weed known as Arabidopsis thaliana that had confirmed hugely necessary for genetics. It used to be effortless to develop, and its time from “seed to seed” was once approximately twenty days.

Rated 4.34 of 5 – based on 36 votes